E2F3 anticorps (AA 150-200)

N° du produit ABIN6992046

Cet anticorps anti-E2F3 est un anticorps Lapin Polyclonal détectant E2F3 dans WB, ELISA, IHC (p) et IF. Adapté pour Humain et Souris.

Aperçu rapide pour E2F3 anticorps (AA 150-200) (ABIN6992046)

Antigène: E2F3

Reactivité: Humain, Souris

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp E2F3 est non-conjugé

Application: Western Blotting (WB), ELISA, Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunofluorescence (IF)

Détail du produit anti-E2F3 anticorps

Épitope: AA 150-200

Specificité: E2F3 antibody is human and mouse reactive. At least three isoforms of E2F3 are known to exist, this antibody will detect only the largest isoform. This antibody is predicted to not cross-react with other members of the E2F transcription factor family.

Purification: E2F3 antibody is affinity chromatography purified via peptide column.

Immunogène: E2F3 antibody was raised against a 15 amino acid peptide near the center of human E2F3. The immunogen is located within amino acids 150 - 200 of E2F3.

Isotype: IgG

Information d'application

Indications d'application: E2F3 antibody can be used for detection of E2F3 by Western blot at 1 - 2 μ,g/mL. Antibody can also be used for Immunohistochemistry starting at 5 μ,g/mL. For immunofluorescence start at 20 μ,g/mL.

Antibody validated: Western Blot in human samples, Immunohistochemistry in human samples and Immunofluorescence in human samples. All other applications and species not yet tested.

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 1 mg/mL

Buffer: E2F3 antibody is supplied in PBS containing 0.02 % sodium azide.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C,4 °C

Stockage commentaire: E2F3 antibody can be stored at 4°C for three months and -20°C, stable for up to one year.

Détails sur E2F3

Antigène: E2F3

Sujet: The E2F transcription factor 3 (E2F3) is a member of a small family of transcription factors that function through binding of DP interaction partner proteins. E2F3 recognizes a specific sequence motif in DNA and interacts directly with the retinoblastoma protein (pRB) to regulate the expression of genes involved in the cell cycle (1). Like the related E2F1 and E2F2, E2F3 is essential for cellular proliferation and progression through the cell cycle (2). Altered copy number and activity of this gene have been observed in a number of human cancers (3).

Poids moléculaire: Predicted: 51 kDa

Observed: 56 kDa

ID gène: 1871

NCBI Accession: NP_001940

UniProt: O00716